Weight gain is a common side effect of antidepressants, but some types cause people to pack on pounds more than others, a new study says.

Bupropion users are 15% to 20% less likely to gain a significant amount of weight than those taking the most common antidepressant, sertraline, res...

A new slow-release pill form of ketamine can quell hard-to-treat depression without producing psychedelic side effects normally associated with the drug, early research suggests.

Patients on the strongest dose of ketamine tablets saw significant improvement in their depression compa...

Roughly 1 in 6 people who stop taking an antidepressant will experience symptoms caused by discontinuing the drug, a new review finds.

However, only 1 in 35 will experience severe symptoms after dropping their medication, researchers report June 5 in The Lancet Psychiatry jou...

People coming off antidepressants often struggle with emotional and social turmoil, especially if they quit their meds cold turkey, a new study reports.

Challenges reported by patients quitting antidepressants included feeling overwhelmed by their emotions, finding social situations less enjoyable, and feeling detached and less empathetic towards others.

"Some symptoms were so sever...

The first postpartum depression pill approved for use in the United States is now available to women who need it, the drug's makers announced Thursday.

Sold under the name Zurzuvae, the medication can quickly ease severe postpartum depression and help women regain their emotional equilibrium following childbirth.

The medication, which is now stocked in specialty pharmacies, can also...

WEDNESDAY, Nov. 8, 2023 (Healthday News) -- A new drug to treat postpartum depression will cost nearly $16,000 for a 14-day course of treatment, a price tag that has doctors worried that some patients won't be able to afford the medication.

Zurzuvae (zuranolone) was first ...

The party drug ketamine has gotten a lot of notice for its potential to help people with severe and persistent depression who haven't responded to other treatments.

But a new study has discovered the drug's effect may be in the heads of patients who take it.

Researchers from Stanford Medicine administered either ketamine or a placebo to 40 patients with depression who were already g...

An inexpensive medication long used for depression and migraines now has a clinical trial to back up its off-label use for another condition that lowers quality of life: irritable bowel syndrome (IBS).

In the study, British researchers found that those taking amitriptyline were almost twice as likely as those taking a placebo to see an improvement in IBS symptoms.

"We were delighted...

Most folks know that certain antidepressants have to be taken for a few weeks before people start seeing improvement, and now a new study sheds light on that delay.

Scientists have discovered this is because of physical changes in the brain that unfold over those first few weeks of using selective serotonin reuptake inhibitors (SSRIs) and lead to greater brain plasticity.

SSRIs incl...

Exercise has been dubbed "nature's antidepressant" by doctors for years, and now a new study confirms the notion.

The finding follows a four-month look at the impact that running had on anxiety and depression when compared to a common antidepressant.

SSRIs (selective serotonin reuptake inhibitors) work by boosting levels of serotonin, a neurotransmitter that's a key player when it c...

A clinical trial designed to test repurposed medications for their impact on fighting COVID-19 has found no benefit to taking the antidepressant fluvoxamine (Luvox) to ease coronavirus symptoms.

The study, led by Duke Clinical Research Institute (DCRI) in partnership with Vanderbilt University, found no symptom improvement in those taking the antidepressant at a dose of 100 milligrams (mg...

If you are a new mom struggling with postpartum depression, taking antidepressants known as selective serotonin reuptake inhibitors (SSRIs) may also bear benefits for your child's development.

That's according to new research that found the medications were associated with improvements in a child's behavior up to five years after birth.

Researchers from the Institute of Psychiatry, ...

Sometimes patients with pancreatic cancer are prescribed the benzodiazepine lorazepam (Ativan) for anxiety, but that may be harming their health.

A new study found this treatment was linked to worse outcomes, with shorter survival times and faster disease progression.

Alternatively, those who took alprazolam (Xanax) had a significantly longer progression-free survival than patient...

Modern antidepressants could be effective for long-term treatment of some patients with bipolar disorder, a new trial suggests.

Current guidelines discourage use of antidepressants in these patients, over concerns that the drugs will trigger a manic episode.

But bipolar patients who remained on antidepressants for a whole year had fewer mood episodes than those who were switched to ...

You've been diagnosed with depression. What's next?

The cornerstone of treatment remains antidepressants, so it's likely your doctor will prescribe one for you, but which one might be best?

You will join millions around the world who struggle with how to treat the mental health disorder. An estimated 3.8% of the global population experiences depression, according to the