Delivering dual-targeted, immune-focused CAR T cancer therapy via a patient's spinal fluid quickly shrank deadly brain tumors, researchers report.

CAR T therapy harnesses the power of the patient's immune system T-cells, which are reprogrammed to seek and destroy a specific protein found on cancer cells.

However, in the new trial -- focused on patients with deadly glioblastomas (...

People who've suffered a moderate to severe traumatic brain injury have a greatly increased risk of brain cancer, a new study of military service members finds.

Brain cancer is relatively uncommon, occurring in fewer than 1% of people in the United States, researchers said.

But service members who had a moderate or severe brain injury were at 90% increased risk for developing malign...

Professional guitarist Christian Nolen took his stage show to an operating room last month, strumming out Deftones tunes for surgeons as they worked to remove a tumor from his brain.

Nolen's performance wasn't just for entertainment -- his guitar playing helped guide the brain surgeons during the delicate operation.

By playing the guitar during an "awake"portion of his two-hour surg...

THURSDAY, Nov. 16, 2023 (Healthday News) -- While childhood cancer is no longer terminal for many, death rates remain higher in Black and Hispanic children, a new government report reveals.

Treatments for these rare cancers have improved drastically in recent decades, and death rates dropped for all children in 2001 -- and kept dropping for another decade.

But over the past 10 years...

A targeted treatment has had unprecedented success in shrinking a rare brain tumor, according to clinical trial results.

These tumors are papillary craniopharyngiomas (PCPs), and the drug combo is called vemurafenib/cobimetinib.

Each of 15 patients who received one or more cycles of targeted therapy responded to treatment, with an average 91% reduction in tumor size, Mass Gene...

Scientists have developed an artificial intelligence (AI) tool capable of deciphering a brain tumor's genetic code in real time, during surgery -- an advance they say could speed diagnosis and personalize patients' treatment.

The researchers trained the AI tool to recognize the different genetic features of gliomas, a group of tumors that constitute the most common form of brain cancer am...

An experimental targeted therapy can dramatically slow the progress of common slow-growing brain cancers, a new clinical trial finds.

The oral drug vorasidenib nearly tripled progression-free survival in patients with grade 2 gliomas compared to placebo, nearly 28 months versus 11 months, according to results presented Sunday at the American Society of Clinical Oncology (ASCO) annual meet...

Brain cancers are notoriously difficult to treat because most chemotherapy drugs can't breach the blood-brain barrier, a microscopic layer of cells that protect the brain from toxins.

But researchers now say they can temporarily open that barrier and get more chemo to brain tumors, using an experimental ultrasound device.

The technology led to a four- to sixfold increase in chemo dr...

A gel applied directly into the brain could offer new hope for patients diagnosed with glioblastoma, the most common malignant brain tumor in adults.

The gel cured 100% of lab mice with glioblastoma when it was applied to the tumor cavity following surgery to remove the cancer, said senior researcher Honggang Cui,...

Getting a single CT scan during childhood doesn't appear to increase a child's risk of a future brain tumor, leukemia or lymphoma, new research finds, but getting four or more scans more than doubles the chances.

CT scans use low-dose radiation, which can damage cells. Past evidence about the risks of cancer from these scans in children 18 and younger was conflicting, researchers said.

A therapy that arms the immune system to find and destroy tumor cells has shown early promise against a rare and aggressive childhood cancer.

Experts called the findings "promising." But they cautioned that much larger studies are needed to see whether and how the treatment can fit into battling the cancer, called neuroblastoma.

Neuroblastoma begins in immature nerve cells, with tum...

Researchers studying patients with low-grade, slow-growing brain tumors have found that more aggressive surgery may extend survival.

The trick to treating low-grade gliomas is to remove as much of them as possible soon after diagnosis, researchers at University of California, San Francisco found.

"Our findings p...

Black patients with head-and-neck cancers have twice the death rates of white patients, and a new study suggests race itself underlies those differences.

"What is unique about our study is it strongly supports the conclusion that Black patients seem to respond to therapy differently than white patients,"said study author