Only Offering Moderna Vaccine

Get Healthy!

Results for search "Clinical Trials".

Health News Results - 170

If you have cancer and you think coronavirus vaccines may do you little good, don't let your hesitation stop you from getting the shots: A pair of clinical trials finds that patients' immune systems ramped up after vaccination.

The findings were presented this week during a virtual meeting of the European Society for Medical Oncology (ESMO Congress 2021).

"We have to vaccinate all ...

New research offers good news for women with an aggressive HER2-positive breast cancer.

A targeted therapy, trastuzumab deruxtecan (T-DXd), sold as Enhertu, triples the length of time that the cancer remains in check when compared with the current gold standard, trastuzumab emtansine (T-DM1).

Both of these drugs are second-line treatment options for HER2-positive breast cancer that...

FRIDAY, Sept. 17, 2021 (HealthDay News) – Researchers hoped to show that the natural antioxidant urate could delay Parkinson's disease progression, but a study completed at Massachusetts General Hospital dashed those expectations.

The trial enrolled nearly 300 individuals recently diagnosed with early Parkinson's disease, which affects the body's motor system. Symptoms such as tremors,...

An experimental Ebola vaccine appeared effective in children and adults in a clinical trial.

Two doses of Johnson & Johnson's Ebola vaccine appear safe, well tolerated and produce a strong immune response in people over the age of 1, according to two just-published papers.

...

COVID-19 vaccine booster shots might not be needed for most people, according to a large international review.

The review -- conducted by a team that included scientists from the World Health Organization and the U.S. Food and Drug Administration -- concluded that current vaccines are effective enough against severe COVID-19, even from the Delta variant, and that booster shots are unnece...

A drug that lowers cholesterol might help save hospitalized patients with COVID-19, a new, small Israeli study suggests.

Researchers at Hebrew University of Jerusalem noted that COVID causes a big buildup of cholesterol, which results in inflammation in cells.

In lab experiments, they found that the cholesterol-lowering drug fenofibrate (TriCor) effectively reduced damage to lung ce...

A new approach to spinal cord stimulation may drastically reduce chronic back pain, a small pilot study suggests.

The study, of 20 patients with stubborn low back pain, tested the effects of implanting electrodes near the spinal cord to stimulate it with "ultra-low" frequency electrical pulses.

After two weeks, 90% of the patients were reporting at least an 80% reduction in their pa...

A new pill specifically designed to prevent migraines appears to do the job, a new clinical trial finds.

Atogepant cut patients' migraine days in half over 12 weeks of treatment, without causing serious side effects, the researchers said.

Experts said the drug, if approved by the U.S. Food and Drug Administration, would give migraine sufferers a welcome new option.

"There's a ...

Racial and ethnic minorities in the United States are severely underrepresented in clinical trials testing cutting-edge treatments for pancreatic cancer, researchers say.

"There are a ton of obstacles to get these patients into clinical trials," said senior author Dr. Jose Trevino, chairman of surgical oncology at Virginia Commonwealth University School of Medicine. "But this is how we're...

An experimental gel has shown early promise in treating the most common form of skin cancer -- hinting at a potential alternative to surgery in the future.

Researchers tested the gel in 30 patients with basal cell carcinoma (BCC), a skin cancer diagnosed in more than 3 million Americans each year. The tumors rarely spread and are highly curable, usually through surgical removal.

Eve...

The pandemic widely disrupted medical care across the United States, but a new study reports that clinical trials testing cancer treatments were able to carry on.

Researchers found that U.S. cancer trials quickly responded to the pandemic in the early months, allowing the studies to get back on track after an initial -- and steep -- drop-off in patient participation.

That was partic...

A drug that eases hallucinations in people with Parkinson's disease may be able to do the same for those with dementia, a new clinical trial finds.

The medication, called Nuplazid (pimavanserin), is already approved in the United States for treating hallucinations and delusions related to Parkinson's.

The new study, published July 22 in the New England Journal of Medicine, ...

A double dose of China's CoronaVac vaccine is 83.5% effective against symptomatic COVID-19, researchers say.

Their phase 3 trial included more than 10,000 people, aged 18 to 59, in Turkey who received either two doses of CoronaVac 14 days apart or an inactive placebo.

An immune response analysis of 981 participants who got the vaccine found that it triggered a strong immune response...

An experimental drug can prevent intestinal damage caused by celiac disease, an early trial has found -- raising hopes that it could become the first medication for the serious digestive disorder.

With celiac disease, the immune system attacks the lining of the small intestine when a genetically susceptible person eats gluten -- a protein found in wheat, rye and barley.

The symptoms...

When antidepressants fail to rein in hard-to-treat depression, the common anesthetic most know as "laughing gas" might be a safe and effective alternative, new research suggests.

The finding follows work with 28 patients struggling with "treatment-resistant major depression," a severe condition that investigators say affects about one-third of all patients - an estimated 17 million Americ...

The U.S. Food and Drug Administration has approved the first new drug to treat Alzheimer's disease in nearly two decades, in a controversial decision that left the agency defending its reputation and its science.

Aduhelm (aducanumab) treats Alzheimer's by clearing out amyloid beta, a sticky protein known to form plaques in the brains of early-stage patients.

It is the first approved...

The first drug ever shown to slow the progression of Alzheimer's disease could be approved by the U.S. Food and Drug Administration on Monday, but experts say that approval will be surrounded by controversy.

In clinical trials, aducanumab showed a 22% reduction in the development of thinking and memory problems associated with Alzheimer's disease, according to a statement from the Alzheim...

Antibiotics do not reduce the risk of hospitalization or death in patients with a lethal lung disease known as idiopathic pulmonary fibrosis, a new study finds.

"We were certainly disappointed in the results," said study co-author Dr. Imre Noth, chief of pulmonary and critical care medicine at UVA Health in Charlottesville, Va. "But we remain hopeful that in further downstream analyses, w...

A newly approved lung cancer drug shows promise in improving survival in patients whose tumors carry a common and tough-to-treat genetic mutation, researchers say.

Sotorasib - brand name Lumakras - was approved May 28 by the U.S. Food and Drug Administration as a targeted therapy for non-small cell lung cancer patients with tumors that express the G12C mutation in the KRAS gene, ...

A twice-daily pill can dramatically reduce the risk of breast cancer recurrence in women who are genetically prone to the disease, researchers report.

The pill - olaparib (Lynparza) - works by blocking a natural enzyme called PARP that normally fixes DNA damage in healthy cells, but in these women actually promotes the growth of cancerous cells.

Early high-risk breast cancer patient...

Moderna plus Pfizer? J&J plus Moderna? There's a new clinical trial underway to assess the safety and effectiveness of mixing different types of booster shots in adults who have been fully vaccinated against COVID-19.

"Although the vaccines currently authorized by the U.S. Food and Drug Administration offer strong protection against COVID-19, we need to prepare for the possibility of ne...

An experimental antibody therapy may help ease skin symptoms from the autoimmune disease lupus, a small preliminary trial suggests.

Researchers found that a higher-dose version of the drug spurred a "clinically meaningful" symptom improvement for 87% of patients after one month.

But they also stressed that the findings are based on a small "phase 1" trial - a type of study designed ...

Moderna's coronavirus vaccine fully protects children aged 12 to 17, the company announced Tuesday.

In a clinical trial that included more than 3,700 young volunteers, there were no cases of symptomatic COVID-19 infection in the two-thirds of participants who received both doses of the vaccine, which translates into an efficacy rate of 100%.

That's the same rate that was reported re...

An experimental injectable drug appears more versatile than existing medications in treating people with different forms of severe, hard-to-control asthma, clinical trial results show.

There are many different types of asthma brought on by many different triggers, and a number of monoclonal antibody medications -- called "biologics" -- have been crafted to target distinct asthma triggers....

Cora Oakley is a rough-and-tumble 4-year-old who loves gymnastics and outdoor activities, particularly if it involves bouncing on a trampoline.

It's hard to tell from looking at her that she was born without an immune system. Kids with this condition can acquire dangerous, life-threatening infections from day-to-day activities as simple as going to school or playing with friends.

"I...

The weight-loss drug Saxenda can keep extra pounds off -- but combining it with exercise brings a bigger payoff, a new clinical trial finds.

The study found that some longstanding advice is valid: Prescription weight-loss drugs work best when used along with -- and not in place of -- lifestyle changes.

Saxenda (liraglutide) is a prescription drug approved in the United States for sp...

Cancer patients most likely to sign up for clinical trials during their treatment include people of color, those with higher incomes and those who are younger, a new study finds.

"This study informs our understanding of who is participating in cancer clinical trials," said study author Dr. Lincoln Sheets, an assistant research professor at the University of Missouri School of Medicine, in...

While COVID-19 research efforts must now shift toward the development of a pill that can prevent serious illness in the recently infected, experts say.

"We need a pill that can keep people out of the hospital, and the time to develop that is right now," Dr. Rajesh Gandhi said during a Thursday media briefing by the Infectious Diseases Society of America. He is director of HIV Clinical Ser...

Like many proud moms, Lisa Stockman-Mauriello of Summit, N.J., is looking forward to exciting milestones in lives of her three sons over the coming months: One will graduate college, one will enter college, and the third will begin high school.

But unlike other moms, it's not guaranteed that she'll be there to experience them.

Lisa, 51, has amyotrophic lateral sclerosis (ALS), a di...

A breakthrough psoriasis drug is better at treating the itchy and painful skin disease than medicines already on the market, according to results from two clinical trials.

There was a "night and day difference" in the results from bimekizumab compared against two established psoriasis drugs, secukinumab (Cosentyx) and adalimumab (Humira), said Dr. Mark Lebwohl, a co-researcher in one of t...

An emerging technology could zap your post-op pain away -- little or no opioids needed.

The technique is called percutaneous peripheral nerve stimulation. It involves inserting a small wire next to a nerve and using a stimulator to deliver a mild electrical current to the affected area, interrupting pain transmission.

A team led by Dr. Brian Ilfeld, of the University of California, ...

A cutting-edge experimental drug cuts nearly in half the risk of death among patients with a rare but aggressive cancer of the eye, new clinical trial data show.

Tebentafusp has now become the first drug shown to improve overall survival in patients with uveal melanoma, said Dr. Antoni Ribas, immediate past president of the American Association of Cancer Research (AACR), in a

  • Dennis Thompson HealthDay Reporter
  • |
  • April 20, 2021
  • |
  • Full Page
  • The magic ingredient in "magic mushrooms" may be at least as effective as standard medication for depression, an early clinical trial suggests.

    The study of 59 patients with major depression tested the antidepressant escitalopram (Lexapro) against psilocybin, which is the psychedelic substance in hallucinogenic mushrooms.

    Over six weeks, it appeared that just two doses of psilocybi...

    One of the most dangerous complications of diabetes is a foot ulcer that won't heal, but now a preliminary study finds that a type of stem cell found in body fat may be a powerful remedy for these severe foot wounds.

    The study included 63 patients with non-healing diabetic foot ulcers who were given injections of cells from their own body fat. Over the next year, the treatment healed the ...

    Marc Baum went through all the usual steps to treat his bladder cancer -- a couple of surgeries, radiation therapy and chemotherapy, all in a three-month period.

    But doctors hope that an extra step -- an experimental vaccine -- will be what keeps Baum's cancer from coming back.

    A vaccine that uses genetics to teach a person's immune system how to precisely target the cancer has prov...

    Fewer clinical trials are being completed during the pandemic, which experts say could affect medical research for decades to come.

    Previously, it was reported that more than 80% of clinical trials were suspended between March 1 and April 26, 2020, with the pandemic cited as the main reason.

    In this study, researchers at Penn State College of Medicine examined more than 117,000 tria...

    A new clinical trial will investigate whether people who are highly allergic or have what's known as a mast cell disorder are at higher risk for a sudden allergic reaction to the Moderna or Pfizer COVID-19 vaccines.

    "The public understandably has been concerned about reports of rare, severe allergic reactions to the Moderna and Pfizer-BioNTech COVID-19 vaccines," said Dr. Anthony Fauci, d...

    Two people in the Johnson & Johnson COVID-19 vaccine trial developed Guillain-Barré syndrome, but it's highly doubtful the vaccine is to blame, according to a just-published case study.

    Although both people were in the same trial, one was given the vaccine and the other was given a placebo of saline solution.

    "That strengthens the possibility that the case in our report may have be...

    It's the question everyone wants answered because reopening the world depends on it: Can coronavirus vaccines stop transmission of the virus?

    Now, 21 universities across the United States are teaming up to find out.

    The project, called Prevent COVID U, was started by the COVID-19 Prevention Network housed at the Fred Hutchinson Cancer Research Center in Seattle.

    The study inc...

    The overall eye health of people with diabetes benefits from preventive drug injections directly into the eyeball, but it's too soon to tell whether such treatment will better preserve their vision long-term, new clinical trial results show.

    Regular injections of aflibercept (Eylea) caused a more than threefold reduction in blood vessel leakage inside the retina, and a more than twofold r...

    Middle-aged adults looking to boost their muscle mass do not need to bulk up on protein, a new study suggests.

    Researchers found that 10 weeks of strength training plus a moderate amount of protein were enough to build muscle in previously sedentary middle-aged people. And extra protein brought no added gains.

    The findings run counter to a common belief among exercisers, said resear...

    Daily insulin jabs can be the bane of existence for people who live with type 2 diabetes, but an investigational once-weekly insulin shot may be a game changer for these folks.

    While the research is still in its early stages, the new drug called basal insulin Fc (BIF) is given once a week and appears to be just as effective at controlling blood sugar (glucose) as insulin degludec, the gol...

    Widely used diabetes and obesity drugs don't increase the risk of breast cancer, a new study indicates.

    The drugs -- called glucagon like peptide-1 receptor agonists or GLP-1 RAs for short -- are effective in treating type 2 diabetes and obesity and in reducing heart disease. But some previous studies have suggested a possible link between them and breast cancer.

    GLP-1RAs include al...

    An antibody infusion being tested for preventing HIV does not seem to thwart most infections -- but its success against certain strains of the virus suggests researchers are on the right track.

    That's the takeaway from a clinical trial that put the antibody, called VRC01, to the test in 2,700 people at high risk of contracting HIV.

    Researchers found that infusions of the antibody ev...

    About 7 out of 10 Alzheimer's patients wound up free of the brain plaques that are a hallmark of the disease after treatment with a potentially breakthrough experimental drug, clinical trial results show.

    The drug, donanemab, also significantly slowed the patients' brain decline, according to findings published March 13 in the New England Journal of Medicine.

    Donanemab diss...

    Financial worries can hamper the success of cancer treatment and raise patients' risk of death, according to a new study that offers the first evidence of such a link.

    "The association we found was very strong, and very concerning," said senior study author Dr. Anurag Singh, director of radiation research at Roswell Park Comprehensive Cancer Center in Buffalo, N.Y. "If you are worried abo...

    Just two weeks of treatment with an experimental drug can delay the onset of type 1 diabetes by several years, researchers report.

    The drug, called teplizumab, is already under review by the U.S. Food and Drug Administration based on earlier evidence of its effectiveness.

    If it gets the green light, it would become the first drug approved for delaying type 1 diabetes in high-risk pe...

    Doctors are testing a decades-old surgical technique as a new way to treat certain stroke patients. And the preliminary results look promising, they say.

    At issue are strokes caused by intracranial atherosclerosis, where blood vessels within the brain become hardened and narrowed.

    Strokes occur when the blood supply to the brain is disrupted, depriving tissue of oxygen and nutrients...

    A clinical trial evaluating the use of convalescent plasma in patients with mild to moderate COVID-19 symptoms has been halted because the treatment didn't benefit them, according to the U.S. National Institutes of Health.

    Convalescent plasma (also called "survivor's plasma") is derived from the blood of patients who have already recovered from COVID-19. It's thought that infusions of the...

    Two new studies suggest that the jury is still out on whether the arthritis drug tocilizumab helps those with severe COVID-19.

    Both reports were published recently in the New England Journal of Medicine. The first, from scientists at the University of California, San Diego, found tocilizumab didn't improve outcomes or reduce the risk of death in patients with severe COVID-19 pneu...