A new interactive map of the United States can show people the risk of leg, foot or toe amputations due to peripheral artery disease (PAD) in their locale.

Mississippi has the highest risk of lower limb amputation, followed by Texas, Louisiana, Alabama and South Carolina, the

There's a glimmer of hope for people afflicted by a rare artery-hardening disease than can lead to amputation.

An existing medication called etidronate appears to help slow the buildup of calcium in arteries that's a hallmark of the illness, which is called arterial calcification due to deficiency of CD73 (ACDC).

ACDC is incredibly rare, affecting less than 1 in every 1 million peop...

People who've lost a leg due to injury or disease are often plagued by what's known as phantom limb pain -- discomfort arising in the area, despite the absence of the limb.

Now, researchers report that people who wear a prosthetic leg after amputation may have that pain eased, as well as improved sensation in their new foot, using spinal cord stimulation.

"We are using electrodes an...

Patients with a common vascular disease that causes blockages in their leg vessels had both worse symptoms and outcomes if they were Black or poor, new research finds.

The study from Michigan Medicine looked at more than 7,000 patients with peripheral arterial disease (PAD) who had a lower extremity bypass operation to improve circulation. PAD involves plaque blocking the vessels that ca...

Cynthia Elford had recently lost her left leg to type 1 diabetes, after a sunburned big toe turned nearly black and forced an amputation.

Now, Elford was being told the same thing was happening in her right leg.

"I went to clip the toenail on the big toe of my right leg and I nipped my skin, just nipped it, and it was enough that it didn't heal,"said Elford, 63, of Hermitage, Pa. "A...

Skeletal remains of a young adult discovered in a remote cave in Borneo appear to be the oldest known case of surgical amputation.

Australian and Indonesian researchers estimate the bones are at least 31,000 years old. It appears that the young adult lost his foot and lower leg in childhood and lived for at least six to nine more years after that, they said.

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