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FRIDAY, Sept. 17, 2021 (HealthDay News) – Researchers hoped to show that the natural antioxidant urate could delay Parkinson's disease progression, but a study completed at Massachusetts General Hospital dashed those expectations.

The trial enrolled nearly 300 individuals recently diagnosed with early Parkinson's disease, which affects the body's motor system. Symptoms such as tremors,...

Movement can be very difficult for people with Parkinson's disease, as shaking and stiffness play havoc with balance, coordination and gait.

There are many different tricks Parkinson's patients can use to improve their walking and avoid injury from a bad tumble -- but a new study reveals that people often have to figure them out on their own, with no help from either a doctor or physical ...

A drug that eases hallucinations in people with Parkinson's disease may be able to do the same for those with dementia, a new clinical trial finds.

The medication, called Nuplazid (pimavanserin), is already approved in the United States for treating hallucinations and delusions related to Parkinson's.

The new study, published July 22 in the New England Journal of Medicine, ...

The brains of people who died from COVID-19 were remarkably similar to the brains of people who die from neurodegenerative diseases such as Alzheimer's and Parkinson's, showing inflammation and disrupted circuitry, researchers report.

"The brains of patients who died from severe COVID-19 showed profound molecular markers of inflammation, even though those patients didn't have any reporte...

Parkinson's disease patients can get symptom relief with deep brain stimulation (DBS) therapy that lasts over the long term, a new study shows.

Over 15 years, patients who received DBS, which requires surgical implantation, had significant improvement in motor symptoms and less need for medication, researchers found.

"Our study, for the first time, supports the efficacy of deep brai...

Parkinson's disease is widely seen as a movement disorder, but it can cause an array of symptoms, including hallucinations. Now a new study has shed light on what is happening in the brain during those disturbances.

The study focused on Parkinson's patients who have so-called presence hallucinations -- a false feeling that another person is nearby.

Researchers found that they were a...

People who suffer a traumatic brain injury (TBI) have a significantly higher risk for stroke for years afterward, U.K. researchers say.

Previous studies have linked brain injury with a long-term risk of neurological diseases including dementia, Parkinson's and epilepsy, and it's been suggested that it's also an independent risk factor for stroke.

This new review of 18 studies from f...

Men with certain sleep problems, like sleep walking, may be at a higher risk of developing Parkinson's disease, a new study suggests.

Among nearly 26,000 men, researchers found those who sleepwalked or had rapid eye movement sleep behavior disorder (RBD) had a four times or higher risk of developing Parkinson's disease compared to those who didn't.

"Presence of parasomnia, such as s...

For helping Parkinson's patients improve their balance and mobility, golf may beat the martial art exercise tai chi, a new, small study reveals.

"Exercise is well-known to treat the symptoms of Parkinson's disease," said study author Dr. Anne-Marie Wills, noting it helps to improve gait, balance and fatigue, while offering a measure of depression relief. Several human and animal studies h...

While scientists still don't know what causes Parkinson's disease, new research shows an association between a drug that some men take for an enlarged prostate condition and a reduced risk of developing the illness.

A team led by scientists at the University of Iowa, working in collaboration with researchers in Denmark and China, found that the drug terazosin and similar medications may h...

While researchers continue to try to find the key that unlocks the cause of Parkinson's disease, new research suggests that what a person eats could make a difference.

Researchers in Canada found a strong correlation between eating either a Mediterranean diet or the MIND diet (which combines elements of the Mediterranean diet and a diet known as Dietary Approaches to Stop Hypertension), a...

People who consume high levels of dietary vitamin C and E may lower their risk for Parkinson's disease by almost a third, a new study suggests.

Foods high in vitamin C include oranges, strawberries, broccoli and Brussels sprouts. Foods high in vitamin E include spinach, collard greens, pumpkin and nuts such as almonds and peanuts.

How might the two nutrients ward off Parkinson's? A...

Social isolation during the coronavirus pandemic may worsen Parkinson's symptoms, researchers report.

They gathered five years of information on the social and emotional well-being, diet and physical activity of 1,500 Parkinson's disease patients. They were most recently surveyed in December 2019.

Those who reported feeling the loneliest got less exercise, were less likely to have a...

If you're a senior who can't smell onions, smoke, chocolate or natural gas, it's time to see your doctor.

Seniors who lose their sense of smell -- which doctors call olfactory dysfunction -- have higher odds of dying from all causes within five years, new research shows. Scientists had previously found a link between olfactory dysfunction and impaired thinking and memory.

"We ...

As the air people breathe gets dirtier, their odds for serious neurological disorders such as Parkinson's disease, Alzheimer's and other dementias rises, new research shows.

The long-term study of more than 63 million older Americans can't prove cause and effect, but does show a strong association between air pollution and brain disorders. The researchers said the link was seen even a...

Caffeine may reduce the risk of Parkinson's disease in people who have a gene mutation associated with the movement disorder, researchers report.

"These results are promising and encourage future research exploring caffeine and caffeine-related therapies to lessen the chance that people with this gene develop Parkinson's," said study author Dr. Grace Crotty, of Massachusetts General H...

A major cause of falls in older people is more common among Parkinson's patients, and monitoring for the condition might lower patients' risks, new research shows.

Ever feel dizzy and lightheaded when you suddenly stand up? It's caused by a sudden drop in blood pressure -- a condition doctors call orthostatic hypotension and it can lead sometimes to fainting and falling down.

...

A drug long used to treat Parkinson's disease may benefit patients with a severe form of age-related macular degeneration (AMD), a small clinical trial suggests.

One of the leading causes of vision loss in older people is a condition called dry macular degeneration. More than 15% of Americans over age 70 have AMD, and 10% to 15% of those cases go on to develop the more sev...

While there are treatments to alleviate symptoms of Parkinson's disease, there is no known cure or preventive drug. But a recent review offers some encouraging findings.

The review found more than 100 clinical trials are underway around the world that are testing various preventive therapies and treatments for the neurodegenerative disorder.

The large number of trials, and ...

People who eat healthfully may be less likely to develop a constellation of symptoms that can precede Parkinson's disease, a large new study suggests.

Researchers found that people who closely adhered to a Mediterranean-style diet were about one-third less likely to develop at least three "prodromal" features suggestive of Parkinson's disease, compared to those who stuck with meat and...

It may be possible to protect Parkinson's patients' brains from further damage by turning off a "master regulator" gene, researchers report.

"One of the biggest challenges in treating Parkinson's, other than the lack of therapies that impede disease progression, is that the disease has already laid waste to significant portions of the brain by the time it is diagnosed," said researche...

People with a history of concussion may face increased risks of certain psychological and neurological conditions, a large new study suggests.

The study of more than 186,000 Canadians found that those who suffered a concussion were more likely to develop any of several conditions, including: attention-deficit/hyperactivity disorder (ADHD); depression or anxiety; Parkinson's disease; o...

Data from a five-year clinical trial is adding to growing evidence that deep brain stimulation (DBS) can slow the ravages of Parkinson's disease.

Researchers at Vanderbilt University Medical Center in Nashville, Tenn., said that the therapy appears to curb any worsening of tremor and other symptoms, as well as lessening a patient's need for medications.

"Parkinson's is relen...

In findings that could pave the way to a new treatment for Parkinson's disease, scientists have figured out how to spur the production of new brain cells in mice.

The advance centers on a protein found in various cells in mice and humans. Researchers found that blocking it in the mouse brain caused certain "support cells" there to transform into specialized neurons that produce the ch...

It often seems the older a person gets, the less they sleep, but new research suggests that inconsistent sleep patterns might predict a future diagnosis of Parkinson's disease.

Researchers who studied 2,930 older men for more than a decade found that those with a particular sleep problem -- called circadian rhythm disruptions -- were three times more likely to develop Parkinson's dise...

At a conference hosted two years ago by the Parkinson's Foundation, many neurologists had a pressing issue on their minds: pot.

"Doctors were saying that the number one question from their patients was, 'Can I use medical cannabis for my Parkinson's disease?'" recalled James Beck, the foundation's senior vice president and chief scientific officer.

The answer isn't a simple ...

In a first, scientists have treated a Parkinson's disease patient with his own skin cells -- repurposing them to become key brain cells that the disease kills off.

Two years after receiving the experimental treatment, the patient has had no adverse effects, his doctors report. His symptoms, meanwhile, have either stabilized or gotten somewhat better.

"The improvement has be...

A type of talk therapy by phone may help treat depression in people with Parkinson's disease, researchers say.

Depression is common in Parkinson's disease patients. It's associated with faster physical and mental decline, but is often overlooked and undertreated.

While cognitive behavioral therapy (CBT) has shown promise in easing depression in people with Parkinson's, many ...

The new coronavirus poses a significant risk to people with Parkinson's disease, and experts say they and their caregivers need to take precautions.

"People living with Parkinson's disease are at high risk if they contract COVID-19, whether they are above age 50 or if they have young-onset Parkinson's disease, which occurs in people younger than 50," said Dr. Frederick Southwick, an i...

People with Parkinson's disease often have eye problems, which can interfere with their daily activities and increase their risk for falls, researchers say.

"It is especially important for people with Parkinson's to have the best vision possible because it can help compensate for movement problems caused by the disease, and help reduce the risk of falls," according to the author of a ...

A spirited game of ping pong may be more than just fun: New research suggests it could quell symptoms in Parkinson's patients.

The small study found that patients with the movement disorder had significant improvements in a wide range of symptoms after taking part in a six-month ping pong exercise program.

"Ping pong, which is also called table tennis, is a form of aerobic e...

Love to cross-country ski? Well, all those days spent striding across the snow-covered wilderness may do more than keep you in great physical shape.

Swedish researchers report that very fit long-distance skiers were about 30% less likely to develop Parkinson's disease during their 20-year study.

The research suggests that any activity that keeps you fit might buffer the...

Rising drug costs are hampering the care of patients with debilitating neurological disorders like Parkinson's disease and Alzheimer's, a new study finds.

Patients are less likely to fill necessary prescriptions as out-of-pocket costs increase, said senior researcher Dr. Brian Callaghan, a neurologist with the University of Michigan, in Ann Arbor.

"It's a pretty predictable ...

A genetic variant associated with Alzheimer's disease increases the risk of dementia in people with Parkinson's disease, researchers say.

The finding could lead to new treatments for dementia in Parkinson's patients, according to the team at Washington University School of Medicine in St. Louis.

Parkinson's disease is a progressive neurological disorder that causes tremors, ...

People who develop Parkinson's disease at a younger age (before age 50) may have malfunctioning brain cells at birth, according to a study that also identified a drug that may help these patients.

At least 500,000 people in the United States are diagnosed with Parkinson's each year. Most are 60 or older at diagnosis, but about 10% are between 21 and 50.

Parkinson's is ...

A drug used to fight chronic myeloid leukemia might also relieve symptoms of Parkinson's disease, a new study finds.

In a phase 2 clinical trial, researchers found that the drug nilotinib (brand name: Tasigna) increased production of dopamine and halted decline in motor function. It was well-tolerated by most participants.

"We found that nilotinib is reasonably safe using d...

Some Parkinson's patients who have a deep brain stimulation device implanted to control their symptoms have reported an odd side effect -- they lost the ability to swim.

Researchers report on the cases of nine patients who were still good swimmers even after they were diagnosed with Parkinson's disease. After they had deep brain stimulation surgery, their Parkinson's symptoms improved...

Ultrasound may provide lasting relief from the involuntary muscle movements that are so debilitating to people with Parkinson's disease and another condition called "essential tremor," a small study concludes.

The treatment is still scarce, but it appears to deliver significant and lasting tremor relief, Italian researchers report.

It's called "focused ultrasound." Though ch...

Former professional soccer players have a significantly increased risk of death from brain diseases such as Alzheimer's and Parkinson's, a new study finds.

Former soccer players were about 3.5 times more likely to die of neurodegenerative diseases than people in the general population, according to a study in Scotland.

"This analysis revealed that risk ranged from a fivefold...

For the first time, scientists have found four spots on your DNA that might determine whether you wield your pen with your left hand.

Of the four gene regions, three are associated with proteins involved in brain development and structure, according to a genetic analysis of about 400,000 people in the United Kingdom, including more than 38,000 left-handers.

The study also fo...

People who have reduced blood flow in their brain due to medical conditions and lifestyle habits may be vulnerable to Parkinson's disease, new research suggests.

Those brain blood flow risk factors -- which also affect heart health -- include prior stroke, high blood pressure, high cholesterol, heart failure, sleep apnea, diabetes and smoking.

The findings suggest that contr...

Can sex help improve the health of a Parkinson's patient?

It might -- at least for some.

So claims a new two-year study that tracked the sexual habits and disease progression among 355 Parkinson's patients.

"This is in line with data showing a close relationship between sexual health and general health, both in healthy individuals and in patients with chronic dis...

Doctors often prescribe anticholinergic drugs for a variety of ills. But a new study suggests they may increase the risk of dementia in older patients.

These medicines include everything from Benadryl (diphenhydramine) to certain antipsychotics and Parkinson's meds. They're used to treat a wide range of other conditions, including depression, chronic obstructive pulmonary disease, ove...

A new study supports the notion that a drug used to control epilepsy and other disorders could make some young people more prone to suicide.

The medicine, pregabalin (Lyrica), comes from a class of drugs called gabapentinoids. Besides their use against epilepsy, these drugs are also used to treat nerve pain and anxiety disorders, as well as symptoms of Parkinson's disease. But accordi...

Struggling with bipolar disorder is hard enough, but now a new study from Taiwan suggests these patients are seven times more likely to develop Parkinson's disease.

But U.S. experts cautioned that the absolute risk of developing Parkinson's -- an incurable movement disease -- is still very low for those with the mood disorder.

"I wasn't surprised [by the study's findings],...

It's a connection few have probably considered, but new research suggests that having your appendix removed may up your risk for Parkinson's disease down the road.

The finding follows an analysis that examined health records for roughly 62 million patients. Of these, about 488,000 had an appendectomy. Among those who had the surgery, just under 1% developed the progressive nervous...

Multiple sclerosis, epilepsy and Parkinson's can be physically taxing conditions, but new research shows they exact a huge financial toll as well.

Over a 12-year period, out-of-pocket costs for Americans with these illnesses jumped, with the biggest increase seen among people with multiple sclerosis (MS). Those patients paid 20 times more for their drugs in 2016 than they did in 2004...

Reading the brain waves that control a person's vocal tract might be the best way to help return a voice to people who've lost their ability to speak, a new study suggests.

A brain-machine interface creates natural-sounding synthetic speech by using brain activity to control a "virtual" vocal tract -- an anatomically detailed computer simulation that reflects the movements of the lips...

It may be possible to restore brain cells damaged by Parkinson's disease and reverse a patient's condition, something no current treatment can do, according to British researchers who conducted potentially groundbreaking clinical trials.

They cautioned the trial was small -- just 41 patients -- and the research is still in its early days. But the results of the approach, which deliver...

The number of people living with Parkinson's disease worldwide could double in the next two decades, experts project.

In a report warning of a possible Parkinson's "pandemic," researchers say the stage is set for cases to surge to 12 million or more by 2040.

What's to blame? In large part, trends that are generally positive: Older age is a major risk factor for Parkinson's, ...